the link between coffee and Parkinson's
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Arnold Schwarzenegger <[email protected]>
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Arnold's Pump Club promotes a healthier lifestyle by sharing studies on the link between coffee and reduced risk of Parkinson's and dementia. The brand welcomes subscribers to their daily email, aiming to make their lives healthier and happier. They also discuss a study on blood NAD⁺ tests and their effectiveness as an aging score.
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Unsweetened Coffee Is Tied to Lower Dementia Risk
A study on more than 200,000 people links unsweetened caffeinated coffee to lower dementia and Parkinson's risk. But adding sugar led to a big change. Here's the catch.
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Today’s Health Upgrade
A popular longevity treatment fails a big test
Can coffee reduce your risk of Parkinson’s and dementia?
How to stop forcing the tasks you dread
Beyond The Headline
The Blood Measure That Doesn’t Work Like an Aging Score
Blood NAD⁺ tests are sold as a window into aging: the idea is that your levels fall over time, but if you take the right supplements, they rise and help you age better.
A new study tested the premise behind that pitch.
Researchers measured whole-blood NAD⁺ across seven groups that included younger and older adults, elite athletes, a longevity cohort, and people completing diet or exercise programs.
To many people's surprise, whole-blood NAD⁺ showed no meaningful difference with age and didn't respond to exercise or dieting.
It did rise when people took nicotinamide riboside, a common NAD⁺ booster. The finding stands out because members of the same team had earlier reported that higher NAD⁺ tracked with healthier aging, and this more rigorous follow-up didn't show that connection.
And the measurement method wasn't broken. The test was sensitive enough to catch the rise from supplements, yet none of the attributes associated with aging moved the number at all.
The findings don't show that NAD⁺ remains stable everywhere in the body, and they don't tell us whether NAD supplements provide any health benefit. Nicotinamide riboside raised blood NAD⁺, but raising the number and improving health are separate questions.
Right now, a blood test only shows whether a supplement raises NAD⁺ in your blood.
Based on this study, it cannot tell you how quickly you're aging or whether you've restored NAD⁺ elsewhere in your body. That alone is reason to be skeptical of any blood NAD⁺ test sold as an aging score, and a reminder that moving a number in your bloodstream is not the same as doing anything for your health.
Together With Cometeer
Is Your Coffee Doing More Than Waking You Up?
You already know your morning cup perks you up. But research suggests it may also support a healthier brain as you age, as long as you drink it the right way.
In one of the largest studies of its kind, researchers followed more than 200,000 adults for about nine years to see whether coffee was associated with neurodegenerative diseases like Parkinson's and dementia.
Unlike many studies, they didn't just count cups. They looked at how people took their coffee, focusing on sweetened, unsweetened, caffeinated, or decaf.
People who drank about 3 cups of unsweetened, caffeinated coffee had roughly a 25% lower risk of dementia and a 29% lower risk of Parkinson's compared to non-coffee drinkers.
Neurodegenerative deaths trended lower too, though that result wasn't strong enough to call conclusive.
Researchers believe coffee's bioactive compounds — caffeine, chlorogenic acids, and polyphenols — have neuroprotective effects, helping reduce inflammation and oxidative stress.
However, decaf coffee didn’t show a protective link, which means caffeine likely plays an important role.
But here’s the catch: once sugar was added, the association between coffee and brain protection vanished, and sweetened coffee showed no significant benefit.
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