The Marker You're Missing: Lp(a)
The genetic heart risk marker everyone should test once
Levels promotes testing for Lp(a), a genetic risk factor for heart disease that is barely affected by diet, exercise, or medication. The company highlights the importance of knowing one's Lp(a) level to inform heart health management. Levels offers a one-time heart test to determine this key marker.
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The Marker You're Missing: Homocysteine
The marker that changes how you think about your other heart markers
Lp(a) is one of the strongest known genetic risk factors for heart disease, and it barely responds to diet, exercise, or most current medications. That's exactly why it's worth testing. Knowing your number can impact how aggressively you and your doctor manage everything else that is in your control, like LDL, blood pressure, and smoking. A high Lp(a) is essentially a signal to tighten the reins on the levers you can move. Since levels stay stable for life, this is a test you take once, not something to add to a rotating panel.
The one-time heart test →
What it is
Lp(a) is an LDL-like particle, but unlike LDL or ApoB, which respond meaningfully to diet and exercise, your Lp(a) level is set almost entirely by genetics.
Why it matters
It's "stickier" than regular LDL, promotes clotting, and triggers inflammation in vessel walls, three separate mechanisms a standard cholesterol test won't show you. Genetic studies that isolate Lp(a)-raising variants find a corresponding jump in heart attack risk, so this is one of the few markers where the science has moved past correlation to established causality. Whether lowering it with medication actually reduces that risk is still being tested in ongoing trials.
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